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Roman Tremmel
Research Group Leader Pharmacogenomics and Digital Health

Dr. Roman Tremmel


Tel +49-711-8101 2061

Major Projects

  • Pharmacogenetics and genomics
  • Implementation of pharmacogenetics testing in the clinics

 

Links

Selected References

Pan, Lu; Shan, Shaobo; Tremmel, Roman; Li, Weiyuan; Liao, Zehuan; Shi, Hangyu et al. (2023): HTCA. A database with an in-depth characterization of the single-cell human transcriptome. Nucleic Acids Res
Swen, Jesse J.; van der Wouden, Cathelijne H.; Manson, Lisanne En; Abdullah-Koolmees, Heshu; Blagec, Kathrin; Blagus, Tanja […] Tremmel, Roman […] et al. (2023): A 12-gene pharmacogenetic panel to prevent adverse drug reactions. An open-label, multicentre, controlled, cluster-randomised crossover implementation study. Lancet
Tremmel, Roman; Nies, Anne T.; van Eijck, Barbara A. C.; Handin, Niklas; Haag, Mathias; Winter, Stefan et al. (2022): Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation. Int J Mol Sci
Zhou, Yitian; Tremmel, Roman; Schaeffeler, Elke; Schwab, Matthias; Lauschke, Volker M. (2022): Challenges and opportunities associated with rare-variant pharmacogenomics. Trends Pharmacol Sci
Tremmel, Roman; Klein, Kathrin; Battke, Florian; Fehr, Sarah; Winter, Stefan; Scheurenbrand, Tim et al. (2020): Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression. Human genetics

Curriculum Vitae

Education and Professional Career

Since 2015

Scientist (Prof. Dr. M. Schwab) at the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology.

2016

PhD thesis (Prof. Dr. U.M. Zanger) “ Bioinformatische Analyse und funktionelle Charakterisierung von strukturellen Genvarianten in ADME-Genen in humaner Leber”

2011

Diploma thesis in the Institute of Genetics at the University of Hohenheim, Stuttgart, Germany (Prof. Dr. rer. nat. Anette Preiss). “Komplementärmutation in Notch und Suppressor of Hairless zur Analyse exogener Su(H)-Aktivität”

2005-2011

Studies in Biology at the University of Hohenheim, Stuttgart, Germany

Research Group

Clinical PGx & Digital Health
PGx Diagnostics