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Dr. rer. nat. Nicole Janssen
Scientist

Dr. Nicole Janssen


Tel +49-711-8101 5646

Major Projects

  • Tumoroid cultures of Colorectal Cancer Patients

Selected References

Nicole Janssen, Lisa Speigl, Graham Pawelec, Heike Niessner, Christopher Shipp Inhibiting HSP90 prevents the induction of myeloid-derived suppressor cells by melanoma cells. Cell Immunol. 2018 May;327:68-76.

Lisa Speigl, Nicole Janssen, Benjamin Weide, Graham Pawelec, Christopher Shipp Prognostic impact of the putative cancer stem cell markers ABCG2, CD133, ALDH1A1 and CD44v7/8 in metastatic melanoma. Br J Dermatol. 2017 Nov;177(5):1447-1449.

Nicole Janssen, Sotirios P Fortis, Lisa Speigl, Christoforos Haritos, Nectaria Sotiriadou, Michael Sofopoulos, Niki Arnogiannaki, Catherine Stavropoulos-Giokas, Amalia Dinou, Sonia A Perez, Graham Pawelec, Constantin Baxevanis, Christopher Shipp Peripheral T cell responses to tumour antigens are associated with molecular, immunogenetic and cellular features of breast cancer patients. Breast Cancer Res Treat. 2017 Jan;161(1):51-62.

Sotirios P Fortis, MSc, PhD student; Michael Sofopoulos, MD; Nectaria N Sotiriadou, PhD; Christoforos Haritos, MD; Christoforos K Vaxevanis, BSc; Eleftheria A Anastasopoulou, PhD; Nicole Janssen, MSc, PhD student; Niki Arnogiannaki, MD; Alexandros Ardavanis, MD, PhD; Graham Pawelec, PhD; Sonia A Perez, Ph.D; Constantin N Baxevanis, PhD Differential intratumoral distributions of CD8 and CD163 immune cells as prognostic biomarkers in breast cancer. J Immunother Cancer. 2017 Apr;5:39. (FREE ARTICLE)
Nicole Janssen, Evelyna Derhovanessian, Ilja Demuth, Fadel Arnaout, Elisabeth Steinhagen Thiessen, Graham Pawelec. Responses of dendritic cells to TLR-4 stimulation are maintained in the elderly and resist the effects of CMV infection seen in the young. J Gerontol A Biol Sci Med Sci. 2016 Sep;71(9):1117-23. (FREE ARTICLE)

Curriculum Vitae

Education and Professional Career

Since 2017

Scientist at the Dr. Margarete-Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany

June 2014–today

PhD Biology, University of Tübingen, Tübingen, Germany; Thesis: “Predicting clinical outcome in melanoma and breast cancer using blood and tumour-based immune biomarkers: a means to monitor anti-cancer immune responses”

2011-2014

M.Sc., molecular cellbiology and immunology, University of Tübingen, Tübingen, Germany; Thesis: „Impact of ageing and a latent infection with Cytomegalovirus on dendritic cell phenotype and function“

2008-2011

B.Sc., Biology, University of Tübingen, Tübingen, Germany; Thesis: „Immunogenicity of the TEL-AML1 fusion peptide: a potential immunotherapeutic target“

Research Group

Tumor Models & Microenvironment